October 5, 2025 11:57 am PT by Jose Rossello, MD, PhD, MHCM - 0 comments
Low calf circumference is a common issue among older adults, often associated with poor muscle mass and increased risk of health complications like multimorbidity. This condition is not solely linked to age, as different groups of older adults with low calf circumference have distinct risk factors. Recognizing and addressing low calf circumference can be crucial Read more…
October 5, 2025 11:57 am PT by Jose Rossello, MD, PhD, MHCM - 0 comments
Skipping meals, especially during early and midlife, is linked to an increased risk of physical frailty in later years, highlighting the importance of establishing regular eating habits well before old age. Maintaining consistent meal patterns in midlife may help preserve muscle strength and overall physical resilience as you age, reducing vulnerability to frailty and its Read more…
October 5, 2025 11:57 am PT by Jose Rossello, MD, PhD, MHCM - 0 comments
A novel selenium supplement using redox-responsive nanoparticles (SeMSNs) has been shown to extend lifespan and delay aging-related decline in multiple organs in aged mice by maintaining calcium balance and regulating the Sik1 pathway. This approach effectively reduces oxidative stress and cellular senescence, improving muscle, kidney, and cognitive functions. These findings highlight selenium’s potential role in Read more…
October 5, 2025 11:57 am PT by Jose Rossello, MD, PhD, MHCM - 0 comments
Impaired upper limb flexibility in the oldest-old is linked to a higher risk of all-cause mortality, particularly when the right side is affected, making it a simple and effective predictor of premature death. Maintaining or improving flexibility may support longevity by reflecting overall physical function and resilience in advanced age. Regular flexibility exercises could therefore Read more…
October 5, 2025 11:57 am PT by Jose Rossello, MD, PhD, MHCM - 0 comments
Long-term use of low-dose aspirin in healthy older adults does not extend disability-free survival, defined as living without dementia or persistent physical disability, and may slightly increase the risk of death. While aspirin did not reduce the incidence of heart attacks or strokes in this group, it did raise the risk of serious bleeding. These Read more…
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